ABSTRACT
Rainbow trout (Oncorhynchus mykiss) are currently consumed as live fish, primarily for catering or consumers, as an alternative to salmon in sashimi or dishes. However, Covid-19 has hampered store and restaurant operations. Therefore, developing suitable processing conditions to extend its shelf life, such as online distribution specifications while enhancing the filets' commercial value, would raise its production value. In this study, we investigated the fish filets salted in a 5% salt solution for 2 days and then smoked at 65 degrees C for 4 h under different storage conditions. As result, the higher rate of salt penetration and water loss in the resolved rigor mortis group was associated with tenderization of the meat compared to the rigor mortis group. Thermal-shrinkage and thermal-induced tissue destruction of the smoked fish filets during processing which affects the appearance, flavor, chewiness and overall acceptability. Nevertheless, according to the results of a consumer-type evaluation, the product characteristics of the fish filets from the resolution of rigor mortis group were consistent with those of the rigor mortis group, except for a weaker aroma. Thus, these results explain the relationship between frozen stored fish and the quality of processed products. The economic concept of regulating and distributing scheduling production between raw materials and finished products in the food industry conveys promising findings that will contribute to developing sustainable food processing systems.
ABSTRACT
COVID-I9 has accelerated the adoption of online learning, and the authors' university (like many others) is settling into a blended learning approach. In this chapter, the authors share their experiences in improving students' self-regulation of online learning. The first learning experience for most students at the Singapore Institute of Technology is in online, self-paced courses in Mathematics, Physics, and Chemistry. Beyond content, these courses provide students opportunities to embrace the 'norm' of self-paced, self-directed online learning and to expose and encourage them to develop self-regulation skills. Students are required to self-assess and refer to different learning resources independently, based on their identified needs. The authors have also developed another intervention based on Zimmerman's self-regulated learning model, guiding students to plan, monitor, and adjust their learning plans and develop self-efficacy through this process. For students to transfer these skills into their actual studies, the authors provide individual coaching sessions to facilitate students' implementation. © 2023, IGI Global.
ABSTRACT
An average person carries 1 to 2 kg of microbes in the alimentary track, including the oral cavity. There are more bacteria in a person's mouth than the total human population in the entire world. Oral health is critical to the general systemic health of an individual. The harmonious co-existence between more than 1000 bacterial species and the host's immune system underpins sustained, long-term homeostasis, the sine qua non of oral health. In a similar manner, global oral health is essential for general population health of the world. Since our last review of this subject in 2019, while significant clinical advances continue, the disparity, lack of prevention, insufficient care, and political unrest have persisted or significantly deteriorated. This review focuses on the following important questions: 1.What is oral microbiome? How to detect, characterize, compare, report, and interpret the results?2.How does oral microbiome affect and respond to local and systemic innate immunity?3.What is the role of oral microbiome in the pathogenesis of diseases of the mouth?4.What are the impacts of oral health or the lack of it at the systemic level?5.Why is oral health important at the population level?6.How can the healthcare providers restore and sustain harmonious co-existence between host and oral microbiome?Copyright © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.
ABSTRACT
Accurately assessing and tracking the progression of liver-specific injury remains a major challenge in the field of biomarker research. Here, we took a retrospective validation approach built on the mutuality between serum and tissue biomarkers to characterize the liver-specific damage of bile duct cells caused by a-naphthyl isothiocyanate (ANIT). We found that carboxylesterase 1 (CES1), as an intrahepatic marker, and dipeptidyl peptidase 4 (DPP-IV), as an extrahepatic marker, can reflect the different pathophysiolo-gies of liver injury. Levels of CES1 and DPP-IV can be used to identify liver damage itself and the inflam-matory state, respectively. While the levels of the conventional serological biomarkers alkaline phosphatase (ALP), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) were all con-comitantly elevated in serum and tissues after ANIT-induced injury, the levels of bile acids decreased in bile, increased in serum, and ascended in intrahepatic tissue. Although the level of c-glutamyl transpeptidase (c-GT) changed in an opposite direction, the duration was much shorter than that of CES1 and was quickly restored to normal levels. Therefore, among the abovementioned biomarkers, only CES1 made it possible to specifically determine whether the liver cells were destroyed or damaged with-out interference from inflammation. CES1 also enabled accurate assessment of the anti-cholestasis effects of ursodeoxycholic acid (UDCA;single component) and Qing Fei Pai Du Decoction (QFPDD;multi-component). We found that both QFPDD and UDCA attenuated ANIT-induced liver damage. UDCA was more potent in promoting bile excretion but showed relatively weaker anti-injury and anti-inflammatory effects than QFPDD, whereas QFPDD was more effective in blocking liver inflammation and repairing liver damage. Our data highlights the potential of the combined use of CES1 (as an intra-hepatic marker of liver damage) and DPP-IV (as an extrahepatic marker of inflammation) for the accurate evaluation and tracking of liver-specific injury-an application that allows for the differentiation of liver damage and inflammatory liver injury.(c) 2021 THE AUTHORS. Published by Elsevier LTD on behalf of Chinese Academy of Engineering and Higher Education Press Limited Company. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
ABSTRACT
Purpose: This paper presents a comprehensive study using bibliometric and social network analysis (SNA) to depict the academic community, research hotspots and the correlation between research performance and social network measurements within Library Hi Tech. Design/methodology/approach: Publications from Library Hi Tech between 2010 and 2022 are reviewed and analysed through coauthorship analysis, co-occurrence analysis, SNA and the Spearman rank correlation test. Findings: The annual number of publications in Library Hi Tech increased from 2016 to 2022, indicating that this research has gradually gained global attention. The USA and China are the most significant contributors to the relevant publications. Scholars in this field mainly engage in small-scale cooperation. Academic libraries, digital libraries, libraries, information technology and COVID-19 were hot topics during the study period. In light of the COVID-19 pandemic, there was a marked increase in research on healthcare. Academic interest in the internet of Things and social media has proliferated recently and may soon attract more attention. Spearman rank correlation analysis shows that research performance (i.e. publication count and citation count) is significantly and positively correlated with social network measurements (i.e. degree centrality, betweenness centrality, closeness centrality and eigenvector centrality) in studies of Library Hi Tech. Originality/value: This paper reveals a systematic picture of the research landscape of Library Hi Tech and provides a potential guide for future research. The relationship between scientific research performance and social network measurements can be objectively identified based on statistical knowledge. © 2023, Emerald Publishing Limited.
ABSTRACT
The outbreak of the novel coronavirus pneumonia and the turbulent international situation in recent years have seriously disrupted the normal operation of the entire supply chain (SC). As an emerging technology, blockchain is characterized by decentralization, reliability, transparency and traceability, which can be effectively applied to solve social, environmental and economic concerns and achieve sustainability of supply chain. However, whether blockchain is suitable for every function of a sustainable supply chain (SSC), or what function is best suited for the application of a set of blockchain criteria, can be viewed as a multi-criteria group decision-making (MCGDM) problem. This paper presents a combined MCGDM technique utilizing the social network analysis (SNA) and Multi-Attributive Border Approximation Area Comparison (MABAC), for selecting an appropriate function of SSCs to implement blockchain technology with Neutrosophic information. The framework gives quantitative consideration to the weight of relevant blockchain criteria and decision makers under high uncertainty. This study can also facilitate the effective allocation of resources and enhance the competitiveness of SSCs in the coordinated planning of various blockchain deployments. © 2022 IEEE.
ABSTRACT
Since the emergence of COVID-19, researchers have documented an increase in cases of anti-Asian racism and hate crimes. Research shows a possible connection between the ‘Chinese virus' discourse of the Trump administration and violence in society (Arora and Kim 2020:387). Drawing from critical discourse studies we explore 2,071 comments from one YouTube video which documents anti-China rhetoric by the Trump administration in order to understand the underlying strategies commenters relied on in their reproduction and defence of this discourse. Findings show the trickle-down influence of Trump's discourse on YouTube commenters, but also ways in which social media created a platform for building solidarity among racist groups, as well as sites of resistance. The authors conclude by suggesting more studies attend to this type of discourse and work to educate people on how to counter it. © 2023, equinox publishing.
ABSTRACT
Alexithymia is associated with adverse developmental outcomes. However, this concept has been criticized for being heavily influenced by Western norms of emotional expression and for potentially pathologizing people from different cultural backgrounds. Furthermore, the widely employed variable-centered study approaches hinder research understanding of real-world alexithymia profiles. Using a person-centered approach, the current study investigated the alexithymia profiles among Chinese college students and tested the profiles' relations with childhood adversity and COVID-19 burnout. Four latent alexithymia profiles were identified. The High I profile (particular difficulty identifying feelings) emerged as a risk profile for childhood adversity and COVID-19 burnout. Our findings illustrate the heterogeneity of the alexithymia construct and represent a significant step toward expanding cross-cultural understanding of alexithymia profiles and their associations with related psychological constructs. When dealing with childhood adversity and COVID-19 burnout, health care programs should consider a specific alexithymia profile defined by difficulty identifying feelings. © 2022 Elsevier Inc.
ABSTRACT
The assembly of modular containers using building information modelling (BIM) technologies was studied. The purpose of this study was to analyse the literature on prefabricated (prefab) houses and explore the concept of creating a digital prototype of a building based on Huoshenshan hospital using Autodesk Revit software. This hospital was constructed to treat Covid-19 patients in early 2020. The article describes the methodology of installing modular containers and assembly structures using BIM technologies for rapid construction. The results of this study showed that building object implementation depends directly on a proper model with a step-by-step mechanism for installation. Due to the supply of prefab structures at the construction site, both initial project cost and project time can be reduced. Prefab house technology demonstrated the high efficiency of using BIM technology in the assembly of Huoshenshan hospital, which was constructed in 10 days. The need for information modelling data exchange with modern technology and systems, which allows the team to become acquainted with the project before installation work starts at the construction site, is investigated.
ABSTRACT
The ongoing COVID-19 pandemic made us re-realize the importance of environmental disinfection in indoor areas. Several studies have documented that the air purification system combining UV light and high-efficiency particulate air (HEPA) filtration can successfully remove the virus from the air. However, UV light cannot penetrate deep into the HEPA, which causes the pathogens inside cannot be killed. In this study, we analyzed the potential of three-dimensional(3D) filter media combining with UV sterilization for the treatment of pathogen aerosols. Through geometric ray analysis, it is concluded that the transmittance attenuation of 3D filter material is linear, while that of ordinary fabric filter material is abrupt, which means UV light combining with common fabric filter can only kill the microorganisms on the surface. In order to prove that 3D filter with UV irradiation can eliminate microorganisms inside the 3D filter, we carried out an experimental verification. The results of the experiment shows that the bactericidal rate increased with UV dose and the k value is 3.75*10-4, much smaller than that in air UV disinfection. This indicates that although it is more difficult to kill pathogens on the surface of fibers than in air, 3D filter material with UV can kill the pathogens inside. © The Authors, published by EDP Sciences. This is an open access article distributed under the terms of the Creative Commons Attribution License 4.0 (http://creativecommons.org/licenses/by/4.0/)
ABSTRACT
Due to the COVID-19 pandemic, hundreds of thousands of campuses worldwide were closed and teachers and students had to switch their teaching and learning activities to fully online mode. Using videoconferences to replace face-to-face teaching was a popular choice. However, during videoconferences, teachers often find it more challenging to engage students in learning. Further, with a large number of lesson videos generated through videoconferencing recordings, the effective use of lesson videos for teachers' professional development needs further exploration. To address these issues, this paper proposes that teachers could consider using dialogic teaching to enhance student learning and engagement. Also, lesson videos should be transformed into corpora to provide suitable cognitive tools enabling teachers' dialogic teaching. © 2022 IEEE.
ABSTRACT
The paper analyzes the assembly process by the example of assembly-modular containers using building information modeling technologies. This paper simulates a 3D model of the Huoshenshan Hospital with a description of the assembly mechanism process based on information modeling of prefabricated buildings. The purpose of this paper is to analyze the sources on prefabricated houses and explore the concept of creating a digital prototype of a building based on Huoshenshan Hospital, using the Autodesk Revit software. The article describes the methodology of installing modular containers and assembly structures using building information modeling technologies to improve rapid construction technology. The study results showed that building object implementation directly depends on a proper model with a step-by-step mechanism for installation, which can reduce the initial project cost due to the supply of prefabricated structures on the construction site, as well as reduce the project time. The prefabricated house technology demonstrated the high efficiency of using information technology in the assembly of the Huoshenshan Hospital, with which the simulated facility was implemented in 10 days. The need for information modeling data exchange with modern gadgets and systems is investigated, which allows one to get acquainted with the object at the construction site before installation work start. © 2022 ICE Publishing: All rights reserved.
ABSTRACT
Objective: To identify the potential biological mechanisms by which Rhodiola crenulata (RC) treats cytokine storm (CS) using network pharmacology, molecular docking, and experimental verification. Method(s): The ingredients and targets of RC were collected from the Organchem database. CS-related genes were collected using the GeneCards and OMIM databases. Cytoscape 3.7.2 software was used to construct the RC-CS network diagram. These data were inputted into the STRING database to construct a protein-protein interaction network. we performed gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes enrichment analysis using DAVID and R software. Molecular docking of the active ingredient and pathway-related targets was carried out using AutoDock Vina and PyMOL, and then a CS model was established in rats induced by lipopolysaccharide for in vivo experimental verification. Result(s): The network pharmacology results showed that kaempferol was the most important active component of RC in the treatment of CS, and IL6 and STAT3 were identified as key targets. Molecular docking results showed that RC active components kaempferol had a good binding ability to IL6/STAT3. At the same time, compared with the model group, different doses of kaempferol could down-regulate the expression of inflammatory factors (P <.05), and protect against systemic inflammatory response multiple organ damage. Conclusion(s): This study preliminarily revealed that RC can prevent and treat CS by regulating the expression of inflammatory factors, inhibiting the systemic inflammatory response induced by lipopolysaccharide, and providing a theoretical basis for the study of its pharmacodynamic material basis and mechanism of action. Copyright © The Author(s) 2022.
ABSTRACT
Declaration de liens d'interets: Les auteurs declarent ne pas avoir de liens d'interets. Copyright © 2022
ABSTRACT
Medical professionals have started favoring the use of non-contact intravenous injection robots owing to their importance during the COVID-19 outbreak. However, there are currently few studies considering the robot's needle insertion angle, and most of the needle insertion operations are performed at a steep angle. This increases the rate of puncture failure, and sometimes causes significant pain in patients depending on their individual differences. Therefore, the intravenous injection of the dorsal hand is performed in this study to investigate the determination of the robot's needle insertion angle. with a focus on the optimization of the measurement data to ensure accuracy in the calculation of the needle insertion angle. First, the space point cloud of the needle insertion area on the dorsal hand is obtained by combining a monocular camera with the linear structured light scanning method , and the dorsal hand plane is obtained via fitting dorsal hand point clouds using the least squares method. During the calibration process for the linear structured light system , the measurement error is eliminated by formulating an error function and using the optimization method to iteratively solve it. Subsequently. the needle insertion angle is determined based on the obtained needle insertion area plane. Finally, experiments are conducted for the accuracy verification of the proposed method. Based on the experimental results, the average error in the optimized structured light plane position is approximately 0. 1 mm, and this serves as a foundation for subsequent automatic injection studies.
ABSTRACT
Objectives: The goal of this article is to evaluate and explain the heterogeneity of the Coronavirus disease 2019 (COVID-19) epidemic in Australia, to offer advice for stopping the current outbreak and preparing for a suitable response to epidemics in the future. Method(s): We conducted a review to analyze the epidemic and explain its variable manifestation across states in Australia. Most COVID-19 cases and deaths were in the states of Victoria and New South Wales due to differences in the governance of the epidemic and public health responses (quarantine and contact tracing) among states. Result(s): Countries could learn from Australia's overall successful response not only through good governance, effective community participation, adequate public health, adequate health system capacity and multisectoral actions but also from the heterogeneity of the epidemic among states. Conclusion(s): A successful response to epidemics in countries with a decentralized administration requires multilevel governance with alignment and harmonization of the response. Copyright © 2022 E-Century Publishing Corporation. All rights reserved.
ABSTRACT
The great anti-epidemic spirit is the spirit of the times formed by all Chinese people in the great struggle against COVID-19 under the leadership of the Communist Party of China. The reason for the spatial transformation of the integration of anti-epidemic spirit education is that the great anti-epidemic spirit is the product of specific space environment. Modern space theory provides a new perspective for the integration of anti-epidemic spirit education.and With the end of the epidemic, the era of the epidemic has changed from the anti-epidemic space to the anti-epidemic spirit education space. The principle of spatial dimension of anti-epidemic spirit education lies in the environment creats people, the anti-epidemic spirit and the spatial environment are mutually embedded and mutually constructed, and the formation of the anti-epidemic spirit is the unity of perceptual cognition and rational cognition.education, and the formation of the anti-epidemic spirit is the unity of perceptual cognition and rational cognition. At the practical level, considering the integration of anti epidemic spirit education from the spatial dimension, we should not only integrate the anti epidemic spirit elements into the multi dynamic spatial environment, but also give full play to the role of multi spatial collaborative education and the supervision role of multi subjects in the spatial environment. © 2022, Editorial department of Chinese Medical Ethics. All rights reserved.
ABSTRACT
Background The coronavirus disease 2019 (COVID-19) has affected approximately 2 million individuals worldwide;however, data regarding fatal cases have been limited. Objective To report the clinical features of 162 fatal cases of COVID-19 from 5 hospitals in Wuhan between December 30, 2019 and March 12, 2020. Methods The demographic data, signs and symptoms, clinical course, comorbidities, laboratory findings, computed tomographic (CT) scans, treatments, and complications of the patients with fatal cases were retrieved from electronic medical records. Results The median patient age was 69.5 (interquartile range: 63.0-77.25) years, and 80% of the patients were over 61 years. A total of 112 (69.1%) patients were men. Hypertension (45.1%) was the most common comorbidity, while 59 (36.4%) patients had no comorbidity. At admission, 131 (81.9%) patients had severe or critical COVID-19, whereas 39 (18.1%) patients with hypertension or chronic lung disease had moderate COVID-19. In total, 126 (77.8%) patients received antiviral treatment, while 132(81.5%) patients received glucocorticoid treatment. A total of 116 (71.6%) patients were admitted to the intensive care unit (ICU), and 137 (85.1%) patients received mechanical ventilation. Most patients received mechanical ventilation before ICU admission. Approximately 93.2% of the patients developed respiratory failure or acute respiratory distress syndrome. There were no significant differences in the inhospital survival time among the hospitals (P=0.14). Conclusion Young patients with moderate COVID-19 without comorbidity at admission could also develop fatal outcomes. The in-hospital survival time of the fatal cases was similar among the hospitals of different levels in Wuhan. © Wolters Kluwer Health, Inc. All rights reserved.